TOX 4370

Molecular Basis of Aging Biology

Course Description

Course information provided by the 2026-2027 Catalog.

This course primarily focuses on the genetic, molecular and cellular basis of aging biology, with an emphasis on how experimental insights obtained from animal and cell models inform our understanding of the aging process. We will also learn about the evolutionary aspect of aging based on comparative studies. Subject matter will include not only what we know about the molecular basis of aging biology but also how we learned it. The course is designed to introduce the conserved pathways and processes that influence aging biology.

Prerequisites BIOMG 2800 or BIOMG 3320 or equivalent.

Last 4 Terms Offered (None)

Learning Outcomes

• Describe at least three principles that are known to have a major impact on the aging process.
• Compare and contrast at least five hallmarks of aging at molecular, cellular, and organismal levels, describe how these hallmarks interconnect to drive age-related decline.
• Explain the major strengths and weaknesses of the common experimental systems used to study aging biology.
• Identify at least three conserved pathways that influence aging based on current research.
• Evaluate primary literature on a chosen topic relates to aging biology.

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