BIOMG 6000

Genomics: Technology, Data, and Applications

Course Description

Course information provided by the 2026-2027 Catalog.

This course introduces omics approaches, which profile genome-wide molecular information across multiple biological layers, including the genome, transcriptome (gene expression), epigenome (e.g., chromatin accessibility and transcription factor binding), and proteome. Students will learn about major omics technologies such as DNA-seq, RNA-seq, ChIP-seq, ATAC-seq, single-cell omics, spatial transcriptomics, and proteomics, and their applications in areas including genomic medicine, biotechnology, and agriculture. The course also introduces foundational computational tools used in genomic data analysis. Students will develop core skills in accessing genomic datasets, visualizing genome-wide information, and performing basic data manipulation and analysis, while learning how biological information is encoded, regulated, and interpreted across genome-wide molecular layers.

Prerequisites Two majors-level biology courses, and one of the following: BIOMG 2800, BIOMG 3300, BIOMG 3350, BIOMG 3310 or BIOMG 3320, or permission of instructor.

Last 4 Terms Offered 2025FA, 2024FA, 2023FA, 2022FA

Learning Outcomes

• Identify and explain genome information encoded at multiple levels including DNA sequence, chromatin structure, transcriptional and postranscriptional regulation, and the proteome.
• Develop rudimentary skills in viewing, acquiring and processing genomic data.
• Devise experiments that take advantage of genomic technologies while keeping study design and sample size in mind.
• Appraise the applications of genomic technologies in health, medicine, agriculture etc.

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